Efficient synthesis of isogranulatimide C, an analogue of the marine G2 checkpoint inhibitor alkaloid isogranulatimide
β Scribed by Evelyne Delfourne
- Book ID
- 113930064
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- French
- Weight
- 164 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0040-4039
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Two series of regioisomeric pyrazolic analogues of the marine alkaloids granulatimide and isogranulatimide were prepared. The synthesis of the first series was based on the condensation reaction of diversely 5-substituted 3-bromoindoles with pyrazole followed by addition of the intermediates on dibr
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