Efficient synthesis of imidazopyridodiazepines from peri annulation in imidazo[1,2-a]pyridine
β Scribed by C. Dechambre; Jean M. Chezal; E. Moreau; F. Estour; B. Combourieu; G. Grassy; A. Gueiffier; C. Enguehard; V. Gaumet; Olivier Chavignon; Jean C. Teulade
- Book ID
- 104252396
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 304 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
In 3-amino imidazopyridines, complete C(5) regiospecificity yielded corresponding TIBO-like derivatives (Β±)-3a, 6a and (Β±)-8a-c. The structures of these polycyclic compounds containing the azaindole moiety were determined by 1D and 2D NMR, and by X-ray crystallography.
π SIMILAR VOLUMES
ethoxycarbonylmethylene)-2,3,4,5-tetrahydroimidazole undergoes annulation with a variety of 1,3-bis-eleetrophiles (a,ll-unsaturated acid derivatives, 13-ketoesters, a, lt-unsaturated aldehydes) to form imidazo[l,2-a]pyridines.
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