Synthesis of methyl (Z)-tetracos-5-enoat
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Gurdyal S. Besra; David E. Minnikin; Paul R. Wheeler; Colin Ratledge
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Article
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1993
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Elsevier Science
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English
⚖ 827 KB
The high molecular weight 2-alkyl-3-hydroxy mycolic acids are key structural components of the cell envelope of pathogenic mycobacteria, such as Mycobacterium tuberculosis. A prime target for drug action would be the initial stages where the biosynthetic pathways diverge from those of ordinary fatty