## Abstract An efficient synthesis of bis(indolyl)methanes through Fe^III^βcatalyzed electrophilic substitution reactions of indoles with various aldehydes in ionic liquid is described. It was found that the ionic liquids involving FeCl~3~Β·6H~2~O were the most efficient catalytic systems, and could
β¦ LIBER β¦
Efficient Synthesis of Bis(indolyl)methanes Catalyzed by Lewis Acids in Ionic Liquids.
β Scribed by Shun-Jun Ji; Min-Feng Zhou; Da-Gong Gu; Shun-Yi Wang; Teck-Peng Loh
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 103 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Sodium tetrafluoroborate (NaBF~4~) was found to catalyze the electrophilic substitution reactions of indoles with aldehydes and ketones under solventβfree conditions to afford the corresponding bis(indolyl)methanes in high yields.