Efficient FeIII-Catalyzed Synthesis of Bis(indolyl)methanes in Ionic Liquids

✍ Scribed by Shun-Jun Ji; Min-Feng Zhou; Da-Gong Gu; Zhao-Qin Jiang; Teck-Peng Loh

• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 89 KB
• Volume: 2004
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/ejoc.200300719

✦ Synopsis

Abstract

An efficient synthesis of bis(indolyl)methanes through Fe^III^‐catalyzed electrophilic substitution reactions of indoles with various aldehydes in ionic liquid is described. It was found that the ionic liquids involving FeCl~3~·6H~2~O were the most efficient catalytic systems, and could be simply recycled without significant loss of activity. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)