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Efficient Synthesis of Bicyclo[3.3.1]nonane Systems via Tandem 1,3-Dinucleophilic Addition of 4-Hydroxy-2-quinolinones to Quinolinium Salts

✍ Scribed by Moghaddam, Firouz Matloubi; Mirjafary, Zohreh; Saeidian, Hamdollah; Foroushani, Behzad Koushki; Nourian, Saghar


Book ID
120616194
Publisher
Taylor and Francis Group
Year
2012
Tongue
English
Weight
303 KB
Volume
42
Category
Article
ISSN
0039-7911

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Herein we report the efficient syntheses of 1,4-disubstituted-2,3-diketopiperazines and 1,4,5-trisubstituted-2,3-diketopiperazines, which feature a tandem reductive amination and acylation. Aliphatic and aromatic primary amines serve as viable nucleophiles under the mild reaction conditions.