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Efficient Synthesis of Arylated Flavones by Site-Selective Suzuki–Miyaura Cross-Coupling Reactions of the Bis(triflate) of 5,7- and 7,8-Dihydroxyflavone

✍ Scribed by Nadi Eleya; Imran Malik; Sebastian Reimann; Kai Wittler; Martin Hein; Tamás Patonay; Alexander Villinger; Ralf Ludwig; Peter Langer

Book ID
102830121
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
663 KB
Volume
2012
Category
Article
ISSN
1434-193X

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Synthesis of Arylated Quinolines by Chem
Synthesis of Arylated Quinolines by Chemo- and Site-selective Suzuki–Miyaura Reactions of 5,7-Dibromo-8-(trifluoromethanesulfonyloxy)quinoline
✍ Nadi Eleya; Ahmed Mahal; Martin Hein; Alexander Villinger; Peter Langer 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 631 KB

## Abstract Arylated quinolines were prepared by Suzuki–Miyaura reactions of 5,7‐dibromo‐8‐(trifluoromethanesulfonyloxy)quinoline. The reactions proceed with excellent site‐selectivity. The first, second and third attack occur at positions 5, 7 and 8, respectively.