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Efficient synthesis of 3-alkyl indoles through regioselective ring opening of epoxides catalyzed by sulfated zirconia

✍ Scribed by Biswanath Das; Ponnaboina Thirupathi; Rathod Aravind Kumar; Kongara Ravinder Reddy


Book ID
119216097
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
143 KB
Volume
9
Category
Article
ISSN
1566-7367

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Ruthenium-catalyzed regioselective synth
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Anilines react with epoxides in dioxane at 180Β°C in the presence of a catalytic amount of a ruthenium catalyst along with tin(II) chloride to afford 2-substituted indoles in moderate to good yields.