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Efficient Synthesis of 2-Substituted-1,2,3-triazoles

✍ Scribed by Kalisiak, Jarosław; Sharpless, K. Barry; Fokin, Valery V.


Book ID
118152030
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
346 KB
Volume
10
Category
Article
ISSN
1523-7060

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ChemInform Abstract: An Efficient Synthe
✍ Frank J. Urban; Ralph Breitenbach 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

An Efficient Synthesis of 6-Substituted 2-(2H-[1,2,4]Triazol-3ylmethyl)-1,2,3,4-tetrahydro-isoquinolines. -Using a bis-alkylation of amine (V) with mesylate (VI) as the key step, title compounds such as (VII)-(IX) are easily prepared. The structure of compound (IV) is proven by X-ray analysis. -(UR