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Efficient Route to 7α-(Benzoyloxy)-3-dioxolane Cholestan-24( R )-ol, a Key Intermediate in the Synthesis of Squalamine

✍ Scribed by Jones, Stephen R.; Selinsky, Barry S.; Rao, Meenakshi N.; Zhang, Xuehai; Kinney, William A.; Tham, Fook S.


Book ID
126087898
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
78 KB
Volume
63
Category
Article
ISSN
0022-3263

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Crystal structure of 3β-benzoyloxy-6α-ch
✍ David K. Wilson; William K. Wilson; Florante A. Quiocho; George J. Schroepfer Jr 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 441 KB

The X-ray crystal structure of 3~-benzoyloxy-6a-chloro-5a-cholest-7-ene (IV) was determined by the heavy atom method and ref'med to R ---0.063 (space group P2s, a --11.364, b = 11.089, c --12.232,/~ = 99.43 °, Z ---2). IV was previously shown to be an important intermediate in the acid-catalyzed iso