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Efficient regioselective synthesis of enantiomerically pure 4-hydroxymethyl-Δ2-thiazoline

✍ Scribed by Fredrik Almqvist; Dom Guillaume; Scott J. Hultgren; Garland R. Marshall

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
197 KB
Volume
39
Category
Article
ISSN
0040-4039

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An Efficient Synthesis of Enantiomerical
An Efficient Synthesis of Enantiomerically Pure Δ- and Δ-Ruthenium(II)-Labelled Oligonucleotides
✍ Eric Meggers; Dirk Kusch; Bernd Giese 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 German ⚖ 747 KB

## Abstract The synthesis of a novel tris(bidentate ligand)ruthenium(II) complex 7 and its efficient tethering to the 5′‐end of Oligonucleotides is described. The resulting Δ‐ and Δ‐isomeric ruthenium(II)‐labelled Oligonucleotides 10a‐‐c and 11a‐‐d were separated either by reversed‐phase HPLC or by