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Efficient Pd-Catalyzed Synthesis of 2-Arylaminopyrimidines via Microwave Irradiation.

✍ Scribed by Henry Q. Zhang; Zhiren Xia; Anil Vasudevan; Stevan W. Djuric


Publisher
John Wiley and Sons
Year
2006
Weight
21 KB
Volume
37
Category
Article
ISSN
0931-7597

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## Abstract magnified image A regioselective Suzuki coupling of 2,6‐dichloronicotinic acid with aryl boronic acids to synthesize 6‐aryl‐2‐chloronicotinic acids is described. Regioselectivity was achieved in aqueous dioxane using the routinely used catalyst Pd(PPh~3~)~4~.