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Efficient Lewis acid-assisted Brønsted acid (LBA) catalysis in the iron-catalyzed Friedel-Crafts alkylation reaction of indoles

✍ Scribed by Jiang, Zhen-Yu ;Wu, Ji-Rong ;Li, Li ;Chen, Xi-Huai ;Lai, Guo-Qiao ;Jiang, Jian-Xiong ;Lu, Yixin ;Xu, Li-Wen


Book ID
111488117
Publisher
Walter de Gruyter GmbH
Year
2010
Tongue
English
Weight
589 KB
Volume
8
Category
Article
ISSN
2391-5420

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✍ Magnus Rueping; Sadiya Raja; Alberto Núñez 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 196 KB 👁 1 views

## Abstract A new enantioselective Brønsted acid‐catalyzed Friedel–Crafts reaction of indole with cyclic imines has been develeoped. This organocatalytic reaction provides for the first time optically active indolindolinone derivatives in high yields and with excellent enantioselectivities (up to 9