## Abstract We analyzed predictive and reactive grip force behavior in 15 patients with Gilles de la Tourette syndrome (GTS) and 15 sex‐ and age‐matched healthy control subjects. Nine patients were without medication; six patients were on medication. In a first experiment, participants lifted and h
Efficient internal pallidal stimulation in Gilles de la Tourette syndrome: A case report
✍ Scribed by Nico J. Diederich; Karin Kalteis; Mara Stamenkovic; Vannina Pieri; François Alesch
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 95 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0885-3185
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✦ Synopsis
Abstract
The usefulness of deep brain stimulation (DBS) of thalamic nuclei in Gilles de la Tourette syndrome (GTS) has recently been advocated. We report on a 14‐month follow‐up study of a patient with intractable GTS in whom bilateral DBS of the internal globus pallidus was carried out. Tic frequency per minute decreased by 73% in the postoperative phase and in particular the vocal tics became less intense. Pronation/ supination bradykinesia of the left extremities was a well‐tolerated, permanent side effect. Pallidal DBS could become a valuable rescue therapy for otherwise intractable GTS. © 2005 Movement Disorder Society
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