HIV-1-based defective lentiviral vectors
โ
Lingbing Zeng; Vicente Planelles; Ziye Sui; Suzanne Gartner; Sanjay B. Maggirwar
๐
Article
๐
2005
๐
John Wiley and Sons
๐
English
โ 302 KB
Background Human monocytes play an important role in mediating human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system (CNS), and monocytes-derived macrophages (MDM) represent a major viral reservoir within the brain and other target organs. Current gene transduction of M