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Efficient gene transfer into murine pancreatic islets using adenovirus vectors

✍ Scribed by Eri Mukai; Shimpei Fujimoto; Fuminori Sakurai; Kenji Kawabata; Manabu Yamashita; Nobuya Inagaki; Hiroyuki Mizuguchi

Book ID: 113691500
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 231 KB
Volume: 119
Category: Article
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2007.01.012

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## Abstract ## Background Establishment of a transient gene delivery system, such as adenovirus (Ad) vectors, into embryonic stem (ES) cells and their aggregation form, embryoid bodies (EBs), is essential for its application in regenerative medicine because the transgene should not be integrated i