𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Efficient enantioselective syntheses of chloramphenicol and (d)-threo- and (d)-erythro-sphingosine

✍ Scribed by E.J. Corey; Soongyu Choi

Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
130 KB
Volume
41
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

The chiral diazaborolidine 1 has been applied to the enantioselective syntheses of chloramphenicol ( 2) and (D)-threo-N-acetylsphingosine (3), a synthetic precursor of the diastereomeric (D)-sphingosines.

πŸ“œ SIMILAR VOLUMES

Enantioselective Synthesis of D-erythro-
Enantioselective Synthesis of D-erythro-Sphingosine and of Ceramide
✍ Radomir Julina; Thomas Herzig; Bruno Bernet; Andrea Vasella πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 German βš– 398 KB

In their synthesis of dihydrosphingosine, Rozrsh and Adum [ 131 observed the formation of a I :1 mixture of two isomeric oxazolidinones resulting from an intramolecular transacylation: under our conditions, however, only 9 was obtained. We thank Prof. Dr. W . Roush for a preliminary communication of