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Efficient derivation of human neuronal progenitors and neurons from pluripotent human embryonic stem cells with small molecule induction.

โœ Scribed by Parsons, Xuejun H. (author);Teng, Yang D. (author);Parsons, James F. (author);Snyder, Evan Y. (author);Smotrich, David B. (author);Moore, Dennis A. (author)


Book ID
120013041
Publisher
MyJoVE Corporation
Year
2011
Tongue
English
Weight
241 KB
Volume
56
Category
Article
ISSN
1940-087X

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The team of Liu et al. generated endoderm-derived human induced pluripotent stem (iPS) cells from primary hepatocytes. 1 However, they generated human iPS cells by using viral transgenes. 1 Clinical applications of human iPS cells require avoiding viral transgenes. On the other hand, the reprogrammi