## Abstract Induced pluripotent stem (iPS) cells are of potential value not only for regenerative medicine, but also for disease investigation. The present study describes the development of a neutrophil differentiation system from human iPS cells (hiPSCs) and the analysis of neutrophil function an
Human motor neuron generation from embryonic stem cells and induced pluripotent stem cells
โ Scribed by M. Nizzardo; C. Simone; M. Falcone; F. Locatelli; G. Riboldi; G. P. Comi; S. Corti
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 295 KB
- Volume
- 67
- Category
- Article
- ISSN
- 1420-682X
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With the advent of induced pluripotent stem cell (iPSC) technology, it is now feasible to generate iPSCs with a defined genotype or disease state. When coupled with direct differentiation to a defined lineage, such as hepatic endoderm (HE), iPSCs would revolutionize the way we study human liver biol
The team of Liu et al. generated endoderm-derived human induced pluripotent stem (iPS) cells from primary hepatocytes. 1 However, they generated human iPS cells by using viral transgenes. 1 Clinical applications of human iPS cells require avoiding viral transgenes. On the other hand, the reprogrammi