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Efficient cyclization of ω-oxo-α,β-unsaturated esters using lithium thiolate-initiated Michael-aldol tandem reaction

✍ Scribed by Masashi Ono; Katsumi Nishimura; Yasuo Nagaoka; Kiyoshi Tomioka

Book ID
104262221
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
247 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

The reaction of to-oxo-(x,13-unsaturated esters with lithium thiolates afforded the Michael-aldol tandem cyclization products in good to perfect stereoselectivity depending on the nature of thiolates.

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