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Efficient and sustained gene transfer in terminally differentiated cells with a lentiviral vector

✍ Scribed by Ulrike Blömer; Tal Kafri; Luigi Naldini; I.M. Verma; F.H. Gage


Book ID
117665675
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
118 KB
Volume
33
Category
Article
ISSN
0959-8049

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## Abstract Gene transfer into neural precursors is a powerful approach to study the function of specific gene products during nervous system development. Here we describe a retrovirus‐based methodology to transduce foreign genes into mouse neural precursors. We used a high‐titer bicistronic retrov