The key synthons 2 and 3 [with suitable protecting groups] of the erythronolide A seco acid (1) have been prepared in an enantiomerically pure form, utilizing a stereoselective osmylation of chiral hydroxy (Z,E)-diene ester 6a and subsequent hydrogenation. Recent interest in macrolide and ionophore
โฆ LIBER โฆ
Efficient and highly stereoselective syntheses of enantiomerically enriched C(1)-C(7) subunits of erythronolides
โ Scribed by Ahmar, Mohammed; Romain, Isabelle; Bloch, Robert
- Book ID
- 127110729
- Publisher
- American Chemical Society
- Year
- 1993
- Tongue
- English
- Weight
- 687 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0022-3263
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