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Efficient amplification and cloning of near full-length hepatitis C virus genome from clinical samples

โœ Scribed by Xiaofeng Fan; Yanjuan Xu; Adrian M. Di Bisceglie

Book ID
116293148
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
380 KB
Volume
346
Category
Article
ISSN
0006-291X

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Full-length complementary DNA of hepatit
Full-length complementary DNA of hepatitis C virus genome from an infectious blood sample
โœ Hideki Aizaki; Yoichiro Aoki; Takashi Harada; Koji Ishii; Tetsuro Suzuki; Seishi ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 129 KB

We constructed a full-length complementary DNA (cDNA) clone of hepatitis C virus (HCV) from a blood sample of an HCV carrier. The blood from the carrier was eventually transfused to a patient who later developed typical posttransfusion hepatitis C. It was also shown to be infectious to chimpanzees.