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Efficient adventitial gene delivery to rabbit carotid artery with cationic polymer–plasmid complexes

✍ Scribed by Turunen, M P; Hiltunen, M O; Ruponen, M; Virkamäki, L; Jr, FC Szoka; Urtti, A; Ylä-Herttuala, S

Book ID
110038340
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
600 KB
Volume
6
Category
Article
ISSN
0969-7128

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✍ Timo M. Pakkanen; Marja Laitinen; Mikko Hippeläinen; Mikko O. Hiltunen; Esko Alh 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 794 KB

## Background: Periadventitial gene therapy is a promising alternative for the treatment of stenosis, vessel wall thickening and other complications in vascular surgery. ## Methods: We compared lacz gene transfer efficiency of dotma: dope (1:1 w/w) plasmid/liposome complexes and adenoviruses in p