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Efficient Addition of Allylsilanes to α,β-Enones Using Catalytic Indium and Trimethylsilyl Chloride.

✍ Scribed by Phil Ho Lee; Dong Seomoon; Sundae Kim; K. Nagaiah; S. V. Damle; Kooyeon Lee


Publisher
John Wiley and Sons
Year
2004
Weight
135 KB
Volume
35
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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## Abstract No base is required for the Mg(II)‐catalyzed conjugate addition of nitromethane to α′‐hydroxy enones in the presence of molecular sieves. Good enantioselectivities are attained using 3 or 4 Å MS and about 10 mol % of Mg(OTf)~2~‐chiral bisoxazoline complexes. Elaboration of the adducts t