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Efficiency of the adaptive response of Escherichia coli to alkylating agents

โœ Scribed by Cairns, John


Book ID
109719062
Publisher
Nature Publishing Group
Year
1980
Tongue
English
Weight
407 KB
Volume
286
Category
Article
ISSN
0028-0836

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The ada+ gene of E. coli is a regulatory gene of the adaptive response to simple alkylating agents. ada mutants are sensitive to both the mutagenicity and toxicity of alkylating agents, and are unable to induce O6-methylguanine DNA methyltransferase and 3-methyladenine DNA glycosylase II. The ada+ g