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Efficiency of polyethylenimines and polyethylenimine-graft-poly (ethylene glycol) block copolymers to protect oligonucleotides against enzymatic degradation

โœ Scribed by Carola Brus; Holger Petersen; Achim Aigner; Frank Czubayko; Thomas Kissel


Book ID
116437216
Publisher
Elsevier Science
Year
2004
Tongue
French
Weight
165 KB
Volume
57
Category
Article
ISSN
0939-6411

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A new synthesis method and degradation o
โœ Yu Liu; Juliane Nguyen; Terry Steele; Olivia Merkel; Thomas Kissel ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 714 KB

Hyper-branched polyethylenimine grafted polycaprolactone block mono-methoxyl poly (ethylene glycol) copolymer (hy-PEI-g-PCL-b-mPEG) was obtained through the conjugation of mPEG-PCL with hyperbranched PEI (hy-PEI) based on the Michael addition. mPEG-PCL was synthesized by ring-opening polymerization