Intratumoral injection of a streptococca
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Noriaki Tanaka; Akira Gouchi; Toshinori Ohara; Tetsuya Mannami; Eiji Konaga; Sad
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Article
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1994
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John Wiley and Sons
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English
⚖ 608 KB
## Background: The preoperative intratumoral injection with ok-432 (picibanil, chugai pharmaceutical co., tokyo, japan), an immunomodulatory agent prepared from an attenuated strain of streptococcus pyogenes, activates the regional immune system and causes degeneration of cancer tissue in carcinoma