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Effects of intradermal administration of streptococcal preparation OK-432 on interferon and natural killer cell activities in patients with oral cancer

โœ Scribed by Sato, Mitsunobu; Yoshida, Hideo; Yanagawa, Tetsuo; Yura, Yoshiaki; Urata, Mitsuru; Atsumi, Masahiro; Hayashi, Yoshio; Tagegawa, Yoshihiro

Book ID
122348860
Publisher
Elsevier
Year
1984
Weight
572 KB
Volume
13
Category
Article
ISSN
0300-9785

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The natural-killer(NK)-cell-mediated cytotoxicity to syngeneic tumor cells can be augmented by in vivo priming and subsequent in vitro challenge with the streptococcal preparation OK432. Supernatants of cocultures of spleen cells with OK432 contained interleukin-2 (IL-2) and interferon (IFN), mainly