Felbamate (FBM) monotherapy was evaluated in 44 patients with uncontrolled partial onset seizures in a unique, single-center, randomized, double-blind, parallel-group trial. During the 56-day baseline peripd, patients were required to have at least 8 seizures and to be receiving only one standard an
Efficacy of felbamate monotherapy
β Scribed by MD Andrew N. Wilner
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 122 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0364-5134
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The crystal structure of 2-methyl-2-phenyl-1,3-propanediol dicarbamate (methylfelbamate), C 12 H 16 N 2 O 4 , contains two independent molecules in the asymmetric unit. The hydrogenbonding scheme is three-dimensional and involves interactions of the type N-HΓ Γ ΓO, C-HΓ Γ ΓO and N-HΓ Γ Γ(arene). Ste
## Abstract ## Objective To develop a clinical pharmacogenetic model to predict the efficacy of methotrexate (MTX) in rheumatoid arthritis (RA). ## Methods Two hundred five patients with newly diagnosed RA and active disease were treated with MTX (initiated at a dosage of 7.5 mg/week and increas