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Efficacy of famciclovir treatment in chronic hepatitis B patients with different mutations at position 552 of the DNA polymerase gene

✍ Scribed by Leonieke M.M. Wolters; Pieter Honkoop; Hubert G.M. Niesters; Robert A. de Man

Book ID: 118568014
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 77 KB
Volume: 28
Category: Article
ISSN: 0168-8278
DOI: 10.1016/s0168-8278(98)80243-2

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## Abstract Lamivudine results in the selection of resistant hepatitis B virus (HBV) variants. Because the surface gene of HBV overlaps completely the polymerase gene, the incidence and profile of surface and polymerase gene mutations were investigated prospectively in chronic HBV patients who were