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Efficacy of class I and II vs class III histone deacetylase inhibitors in neuroblastoma

โœ Scribed by Timothy B. Lautz; Jessica A. Naiditch; Sandra Clark; Fei Chu; Mary Beth Madonna


Book ID
116689668
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
374 KB
Volume
47
Category
Article
ISSN
0022-3468

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Histone deacetylase inhibitors (HDACi) suppress cancer cell growth, inflammation, and bone resorption. The aim of this study was to determine the effect of inhibitors of different HDAC classes on human osteoclast activity in vitro. Human osteoclasts generated from blood mononuclear cells stimulated