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Effects ofValeriana OfficinalisExtracts on [3H]Flunitrazepam Binding, Synaptosomal [3H]GABA Uptake, and Hippocampal [3H]GABA Release

✍ Scribed by José G. Ortiz; Jennifer Nieves-Natal; Pedro Chavez


Book ID
110422178
Publisher
Springer
Year
1999
Tongue
English
Weight
525 KB
Volume
24
Category
Article
ISSN
0364-3190

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The effects of ascorbic acid on the synaptosomal uptake of r3H]MPP+, [3H]dopamine, and [I4C]GABA were examined in attempts to understand the mechanism of ascorbic acid attenuation of MPTP neurotoxicity. [3HJDopamine uptake was increased at lower levels (0.01 and 0.1 mM) and decreased at higher level