Effects of phenytoin on cell-mediated im
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Yutaka Okamoto; Keiji Shimizu; Kazuyoshi Tamura; Yasuyoshi Miyao; Masanobu Yamad
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Article
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1988
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Springer-Verlag
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English
⚖ 387 KB
The effects of phenytoin on cellular immunity were examined in murine models. Fresh splenocytes were obtained from mice which had received 1 mg/day of phenytoin i.p. for 28 days. The serum concentration of phenytoin in these animals was 10-20 micrograms/ml. The proliferative response of splenocytes