BACKGROUND. Inhibitors of 5␣ reductase (5␣R), the enzyme that converts testosterone to dihydrotestosterone (DHT), have been shown to retard the growth of hyperplastic prostates. This study evaluates the effects of the 5␣R inhibitor, epristeride, on cultured stromal and epithelial cells from benign,
Effects of various pesticides on human 5α-reductase activity in prostate and LNCaP cells
✍ Scribed by Susan Lo; Isabella King; Axel Alléra; Dietrich Klingmüller
- Book ID
- 116919553
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 416 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0887-2333
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Epidemiological studies strongly support the contention that surgical castration prior to age forty prevents both benign prostatic hypertrophy (BPH) and prostate cancer. 5 alpha-Reductase deficiency in humans, an experiment of nature, is an uncommon genetically transmitted disorder in which prostate
BACKGROUND. Prostate trophism depends on DHT formed from T by the enzyme 5␣-R. Two 5␣-R isoforms with different biochemical characteristics have been cloned. Also estrogens might contribute to the prostate growth; however, their intraglandular formation by the enzyme aromatase is still debated. The