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Partitioning of 5α-dihydrotestosterone and 5α-androstane-3α, 17β-diol activated pathways for stimulating human prostate cancer LNCaP cell proliferation

✍ Scribed by Eva H. Nunlist; Igor Dozmorov; Yuhong Tang; Rick Cowan; Michael Centola; Hsueh-Kung Lin


Book ID
116697299
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
448 KB
Volume
91
Category
Article
ISSN
0960-0760

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## Abstract Androgen and androgen receptor (AR) are involved in growth of normal prostate and development of prostatic diseases including prostate cancer. Androgen deprivation therapy is used for treating advanced prostate cancer. This therapeutic approach focuses on suppressing the accumulation of