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Effects of Variation in Drug Elimination on Five Methods for Assessing Zero-Order Drug Absorption Rates

✍ Scribed by Haiyung Cheng; William J. Jusko


Book ID
110341739
Publisher
Springer US
Year
1990
Tongue
English
Weight
544 KB
Volume
07
Category
Article
ISSN
0724-8741

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Effect of using an incorrect elimination
✍ John G. Wagner πŸ“‚ Article πŸ“… 1984 πŸ› John Wiley and Sons 🌐 English βš– 363 KB πŸ‘ 2 views

Some authors have used an elimination rate constant derived from one theophylline treatment (e.g. the elixir) to apply the Wagner-Nelson method to concentration-time data from another treatment (e.g. a sustained-release form). Since there is considerable intrasubject variation in the elimination rat