Synthetic studies on reidispongiolide A,
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Satoshi Akiyama; Eisuke Toriihara; Kazushi Suzuki; Toshiaki Teruya; Kiyotake Sue
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Article
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2009
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Elsevier Science
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French
โ 265 KB
The C11-C22 and C23-C35 segments 2 and 3 of reidispongiolide A (1), an actin-depolymerizing marine macrolide, were synthesized enantioselectively in 12 steps from (R)-glycidyl trityl ether and in 12 steps from chiral ketone 15, respectively.