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Effects of tyrosinase activity on the cytotoxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol in melanoma cells

โœ Scribed by Prezioso, Joseph A.; Epperly, Michael W.; Wang, Nu; Bloomer, William D.


Book ID
123195793
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
662 KB
Volume
63
Category
Article
ISSN
0304-3835

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The in vivo antimelanoma effect of 4-S-c
โœ Takako Miura; Kowichi Jimbow; Shosuke Ito ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 466 KB

Phenolic melanin precursors can be utilized for the development of anti-melanoma agents. The sulphur homologue of tyrosine, 4-S-cysteinylphenol (CP) and its decarboxylation product, 4-S-cysteaminylphenol (CAP) were shown to be substrates of melanoma tyrosinase, forming melanin-like pigment. Both, bu