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Effects of truncal vagotomy and partial gastrectomy on the pharmacokinetics of propranolol enantiomers in dogs

✍ Scribed by Hans G. Schaefer; Douglas Harrison; Michael P. Hocking; Jobst Limberg; Hartmut Derendorf


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
326 KB
Volume
79
Category
Article
ISSN
0022-3549

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## Abstract In order to determine the potential pharmacokinetic drug interaction between ranitidine and diltiazem (DTZ), each of ten male beagle dogs, age 2Β·7–4Β·0 years, weight 13–16 kg, received a single oral dose of sustained release DTZ with and without previous multiple oral doses of ranitidine