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Effects of tranylcypromine enantiomers on monoamine uptake and release and imipramine binding

โœ Scribed by J. Tuomisto; D. F. Smith

Book ID
105136735
Publisher
Springer
Year
1986
Tongue
English
Weight
484 KB
Volume
65
Category
Article
ISSN
1435-1463

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Effects of tranylcypromine on serotonin
Effects of tranylcypromine on serotonin content and monoamine oxidase activitity of the human blood platelet
โœ Gregory F. Oxenkrug; Richard Balon; Roy B. McCauley; Iain M. McIntyre ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 256 KB ๐Ÿ‘ 1 views

Inhibition (>80 per cent) of platelet monoamine oxidase (MAO-B type) and an increase of platelet serotonin content were observed after tranylcypromine administration. It is suggested that the increase in platelet serotonin reflects MAO-A inhibition, which may be correlated with antidepressant and hy