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Effects of tolcapone on working memory and brain activity in abstinent smokers: A proof-of-concept study

✍ Scribed by Ashare, Rebecca L.; Wileyto, E. Paul; Ruparel, Kosha; Goelz, Patricia M.; Hopson, Ryan D.; Valdez, Jeffrey N.; Gur, Ruben C.; Loughead, James; Lerman, Caryn

Book ID
121442976
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
498 KB
Volume
133
Category
Article
ISSN
0376-8716

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## Abstract Acute psychosocial stress in humans triggers the release of glucocorticoids (GCs) and influences performance in declarative and working memory (WM) tasks. These memory systems rely on the hippocampus and prefrontal cortex (PFC), where GC‐binding receptors are present. Previous studies r