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Effects of the α4β2 Partial Agonist Varenicline on Brain Activity and Working Memory in Abstinent Smokers

✍ Scribed by James Loughead; Riju Ray; E. Paul Wileyto; Kosha Ruparel; Paul Sanborn; Steven Siegel; Ruben C. Gur; Caryn Lerman

Book ID: 119198518
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 526 KB
Volume: 67
Category: Article
ISSN: 0006-3223
DOI: 10.1016/j.biopsych.2010.01.016

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## Abstract Acute psychosocial stress in humans triggers the release of glucocorticoids (GCs) and influences performance in declarative and working memory (WM) tasks. These memory systems rely on the hippocampus and prefrontal cortex (PFC), where GC‐binding receptors are present. Previous studies r