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Effects of thromboxane synthetase inhibitors on aggregation of rabbit platelets

โœ Scribed by Jun Naito; Hidetada Komatsu; Arao Ujiie; Shuichiro Hamano; Tetsuhiro Kubota; Masami Tsuboshima

Book ID
115877919
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
523 KB
Volume
91
Category
Article
ISSN
0014-2999

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The pharmacokinetics and pharmacologic effects of a potent, selective inhibitor of thromboxane synthetase, CV-4151 [(E)-7-phenyl-7-(3-pyridyl)-6-heptenoic acid] on prostanoid formation and platelet aggregation were studied in 42 healthy male volunteers. The drug was well tolerated. After oral admini