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Effects of a selective inhibitor of thromboxane synthetase on human blood platelet behaviour

✍ Scribed by S. Heptinstall; J. Bevan; S.R. Cockbill; S.P. Hanley; M.J. Parry


Book ID
119034438
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
836 KB
Volume
20
Category
Article
ISSN
0049-3848

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The pharmacokinetics and pharmacologic effects of a potent, selective inhibitor of thromboxane synthetase, CV-4151 [(E)-7-phenyl-7-(3-pyridyl)-6-heptenoic acid] on prostanoid formation and platelet aggregation were studied in 42 healthy male volunteers. The drug was well tolerated. After oral admini