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Effects of thein vivoAdministration of Recombinant Human Granulocyte Colony-stimulating Factor Following Cytotoxic Chemotherapy on Granulocytic Precursors in Patients with Malignant Lymphoma1

✍ Scribed by Ema, Hideo ;Suda, Toshio ;Sakamoto, Shinobu ;Tomonaga, Takafumi ;Tsunoda, Jun-ichi ;Muroi, Kazuo ;Komatsu, Norio ;Miwa, Akiyoshi ;Ohsaka, Akimichi ;Yoshida, Minoru ;Motoyoshi, Kazuo ;Takaku, Fumimaro ;Miura, Yasusada


Book ID
108578824
Publisher
Wiley (Blackwell Publishing)
Year
1989
Tongue
English
Weight
353 KB
Volume
80
Category
Article
ISSN
0910-5050

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## Abstract Cycling intensive chemotherapy currently used to treat pediatric solid tumors induces severe neutropenia. Prolonged neutropenia is a major risk factor for septic death which occurs in up to 5% of febrile or septic neutropenic episodes. We treated 18 neutropenic pediatric cancer patients