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Effects of the tumor promoter 12-O-tetradecanoylphorbol 13-acetate on peroxisomal activities and enzyme activities involved in lipid metabolism in rat liver

✍ Scribed by Niels Aarsaether; Richard Fosse; Asle Aarsland; Rolf Kristian Berge


Book ID
115740358
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
898 KB
Volume
1042
Category
Article
ISSN
0005-2760

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Transcription induction of c-Ki-ras with
✍ Sai On Chan; Susanna Siu Chun Wong; Desmond Chak Yew Yeung πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 776 KB

Results from nuclear run-off assays show that exposure of hepatocytes and Reuber H35B hepatoma cells to the tumour promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), leads to enhanced transcription of c-Ki-ras gene. This increase in transcription in turn results in an accumulation of the function