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Effects of the Pit1 mutation on the insulin signaling pathway: implications on the longevity of the long-lived Snell dwarf mouse

โœ Scribed by Ching-Chyuan Hsieh; James H. DeFord; Kevin Flurkey; David E. Harrison; John Papaconstantinou


Book ID
114096235
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
398 KB
Volume
123
Category
Article
ISSN
0047-6374

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โœ G. Fuhrmann; E. Kempf; Dr. A. Ebel ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 736 KB

Effects of growth and thyroid hormone therapy on central cholinergic neurotransmission has been followed in the cholinergic-deficient Snell dwarf mouse. Growth hormone and thyroxine can reverse the neurotransmission impairment even in adulthood. Furthermore, it appears that in the dwldw mouse, hormo