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Effects of the obese gene product on body weight regulation in ob/ob mice

โœ Scribed by Pelleymounter, M.; Cullen, M.; Baker, M.; Hecht, R; Winters, D; Boone, T; Collins, F

Book ID
121449519
Publisher
American Association for the Advancement of Science
Year
1995
Tongue
English
Weight
1023 KB
Volume
269
Category
Article
ISSN
0036-8075

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โœ R. R. French; D. A. York ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Springer ๐ŸŒ English โš– 719 KB

Adenylate cyclase activity was determined using a purified plasma membrane fraction prepared from isolated adipocytes by a Percoll gradient centrifugation procedure. The activation of adenylate cyclase by isoprenaline was reduced by approximately 50% in membranes from obese mice, although no reducti