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Effects of the lipid peroxidation product 4-hydroxynonenal on the aggregation of human platelets

✍ Scribed by J.S. Hurst; T.F. Slater; J. Lang; G. Juergens; H. Zollner; H. Esterbauer


Book ID
113136998
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
773 KB
Volume
61
Category
Article
ISSN
0009-2797

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i y ; 11 Life Sciences Division, Ceri 4-Hydroxynonenal (HNE) is produced during peroxidation of polyunsaturated fatty acids. It exerts a chemokinetic effect on human polymorphonuclear leukocytes (PMN). Investigations of this mechanism were performed. The results indicate that [3H]-HNE binding to PMN